Damage to testicular function after radiation, chemotherapy or hormone treatment; or devascularization as a consequence of hernia surgery.

An oocyte at prophase of meiosis I, (i.e. an oocyte at the germinal vesicle (GV)-stage.)

The attachment and subsequent penetration by a zona-free blastocyst into the endometrium, but when it relates to an ectopic pregnancy, into tissue outside the uterine cavity. This process starts 5 to 7 days after fertilization of the oocyte usually resulting in the formation of a gestation sac.

The number of gestational sacs observed divided by the number of embryos transferred (usually expressed as a percentage, %).

A sequence of procedures that involves extracorporeal fertilization of gametes. It includes conventional in vitro insemination and ICSI.

A sequence of laboratory procedures that enable extracorporeal maturation of immature oocytes into fully mature oocytes that are capable of being fertilized with potential to develop into embryos.

Intentional loss of an intrauterine pregnancy, through intervention by medical, surgical or unspecified means. (See induced embryo/fetal reduction.)

An intervention intended to reduce the number of gestational sacs or embryos/fetuses in a multiple gestation.

A disease characterized by the failure to establish a clinical pregnancy after 12 months of regular, unprotected sexual intercourse or due to an impairment of a person’s capacity to reproduce either as an individual or with his/her partner. Fertility interventions may be initiated in less than 1 year based on medical, sexual and reproductive history, age, physical findings and diagnostic testing. Infertility is a disease, which generates disability as an impairment of function.

A professional intervention with the intention to mitigate the physical, emotional and psychosocial consequences of infertility.

A cycle in which the woman receives specific medication for ovarian stimulation or in which cycle monitoring is carried out with the intention to treat, irrespective of whether or not insemination is performed, follicular aspiration is attempted in an ovarian stimulation cycle or whether egg(s) or embryo(s) are thawed or transferred in a frozen embryo transfer (FET) cycle.

A group of cells attached to the polar trophectoderm consisting of embryonic stem cells, which have the potential to develop into cells and tissues in the human body, except the placenta or amniotic membranes.

A couple or person who seek(s) to reproduce with the assistance of a gestational carrier or traditional gestational carrier.

A procedure in which laboratory processed sperm are placed in the cervix to attempt a pregnancy.

A procedure in which laboratory processed sperm are placed in the uterus to attempt a pregnancy.

A state of reproduction in which an embryo has implanted in the uterus.

A procedure in which a single spermatozoon is injected into the oocyte cytoplasm.

A surgical method for inducing ovulation in females with anovulatory or oligo-ovulatory polycystic ovarian syndrome, utilizing either laser or electrosurgery.

A birth weight greater than the 90th centile of the sex-specific birth weight for a given gestational age reference. When reporting outcomes, the reference criteria should be specified. If gestational age is unknown, then the birth weight should be registered.

A high number of white blood cells in semen above the upper reference limit. When reporting results, the reference criteria should be specified.